“Dr. Ali, he complains of pain in the chest,” the mother of a six-year-old boy told me at the first consultation.
“Does he have a cold?” I asked, looking at the handsome boy studying my face.
“Yes, but that was some weeks ago. He also complained of the chest problem before he had that cold.”
“Did he ever suffer from asthma?” I asked.
”No.”
“Wheezing?”
“No.”
“Headaches?”
“Yes, but why would that cause chest pain?”
“Does he talk about chest discomfort when he seems overactive?”
“Yes.”
“Do you think he is anxious when he has chest discomfort?’
“No, maybe yes.” She looked puzzled.
“His pediatrician never mentioned that he has a heart murmur, did he?”
“No.”

Stress and Anxiety Among Children

It is a mark of our time that I recognize the problems of stress and anxiety among children with increasing frequency. Children are intelligent and perceptive. When parents are stressed and anxious it is not altogether unexpected that children will be affected by it. But for a child to complain of chest pain due to stress is a different matter altogether. When first encountered by this, I was moved to share this with others in a video article in my Science, Health, and Healing Video Encyclopedia (available at my YOU TUBE channel, enter “Majid Ali, M.D.” on youtube.com.)

Children are fast learners. They are also great copycats. When they see adults breathe out slowly they copy it with minimal coaxing. So I recommend Limbic Breathing for them (for details, see my DVD entitled “Limbic Breathing” available at http://majidali.com)

Limbic Breathing for Asthma

I first thought of teaching Limbic Breathing to children in the mid-1980s. I described my earlier experiences in The Cortical Monkey and Healing (1990), available at http://majidali.com) For the general interest of readers, I reproduce here some text from that volume. Read more at   http://wiki-medical.org/limbic_breathing_children.htm

“Sandra was only 19 months old

Majid Ali, M.D.
+
The Video Encyclopedia of Science, Health, and Healing (SHH) is a worldwide public health education service. It was organized to provide guidelines for enlightened and healthful living, natural healing from spiritual and cellular traumas. In founding and developing this video encyclopedia, I present information that is easy to understand, easy to access, untainted by corporate influences, and free for people of all ages and in all regions of the world. Specifically, it serves individuals interested in:

☞ Simple, short, and straightforward answers to health questions
☞ A program of personal guidelines for healthful aging
☞ An e-learning program in health sciences
☞ An e-learning program for disease prevention
☞ A program for learning how to be one’s own doctor for disease prevention and reversal of chronic disease
☞ A program of initial education for persons interested in careers in the healing arts

It is suggested that the individuals with any of the above objectives begin with the following two video segments of the encyclopedia:

☞ Introduction to SHH encyclopedia – Part 1
☞ Introduction to SHH encyclopedia – Part 2

Read more at   http://wiki-medical.org/shh_introduction.htm

Majid Ali, M.D.

Cancer, in essence, is evolution in reverse. Nature took about one billion years to evolve modern life—from hydrogen-nitrogen bonding to amino acids synthesis to RNA make-up to DNA replication. Cancer is evolution in reverse—respiratory to fermentative shift in ATP generation—developing in a millionth of a nanosecond or so on the evolutionary time scala. Your writers have done a great service to readers in presenting a most informative synthesis of recent advances in the field. I might point out that the reversal of evolutionary steps in cancer was the center piece of the oxygen model of cancer which I first published in 1994. I wrote two volume of Oxygen, the Crab, and cancer (2007) to present the model in detail, as well as to explain its clinical implications.

The Oxidative Model of Cancer

In 1995, I proposed the oxidative model of cancer, which holds that oxidosis (accelerated oxidative stress) is the common denominator in all known factors that have been implicated in the cause of cancer. Oxidosis from any and all causes is also the single most important mechanism for sustaining and perpetuating the malignant cellular replication.1

In 2001, looking through the prism of oxygen homeostasis, I extended the my oxidosis model to put forth my oxygen model of cancer. I propsed that cancer is destructive behavior of cells incited and perpetuated by many factors that cumulatively lead to anomalous oxygen signaling. It has six other principal characteristics:

1. Respiratory-to-fermentative (RTF) shift in ATP production—regression to primordial cellular energetics, in the current context);
2. Production of prodigious quantities of organic acids— lactic acid, as well as other Krebs cycle intermediates;
3. Creation of a cocoon of coagulated proteins around malignant cells to exclude functioning host immune cells and their soluble defense molecules;
4. Uncontrolled cellular replication that disrupts local tissue architecture;
5. Colonization of distant tissues in which the destructive behavior of neoplastic cells continues; and 6. Under certain conditions, a cancer cell can be coaxed to alter its behavior

A Pathologist’s Perspective

During my 29 years of work as a hospital pathologist, I conservatively estimate I assumed the responsibility for diagnosing over 75,000 malignant neoplasms and followed the clinical course of many of those cases. That experience was rewarding. It gave me a clear sense of the biology of diverse cancers, as well as the clinical outcomes achievable with the mainstream therapies. During the last two decades, my colleagues at the Institute and I participated in the clinical management of over 2,000 cases of cancer. That experience has been disconcerting, largely because it was not possible to clearly delineate the long-term efficacy of our integrative therapies. Most of those patients concurrently received immunosuppressive therapies— chemotherapy, radiotherapy and others — that countered the integrative oxystatic therapies which we prescribed. Another common problem has been the financial burden of integrative therapies on patients, since insurance carriers nearly always refuse to cover such therapies, seriously compromising the continuity of care. Read more at   http://wiki-medical.org/cancer_evolution_in_reverse.htm

My own ecologic thinking, as I recall it, began one day in 1969. As a pathology resident, I received a large basin brimming with a messy inflamed and distended colon with copious bloody fecal matter spilling out of some tears in its wall. It was not much fun to clean that bowel and take tissue samples for preparing microscopic slides. The next day I examined the slides and observed the expected microscopic features of ulcerative colitis: acute and chronic inflammation, dead and dying immune and other types of cells, ulceration of the lining mucosa, disruption of the general architecture of the colon wall, and pockets of pus. After finishing my study, I took the case to one of my professors. He examined the slides and agreed that it was a case of ulcerative colitis.

The next day, something unexpected happened. Without purpose, I picked another slide of that colon, looked at it, and chanced upon a cluster of large, pale cells forming a discrete round structure. Such a formation is called a granuloma and is considered diagnostic of Crohn’s colitis. “Look at that!” I said to myself in surprise. “Now, that granuloma makes it Crohn’s colitis, doesn’t it? Yesterday it was ulcerative colitis. Today it seems to be Crohn’s colitis. Interesting!” I marked the microscopic field with ink and took the slides to a second professor, since the first one was out of the department. He looked at the case and readily diagnosed Crohn’s colitis.

The next day as I prepared to carry the slides to one of the secretaries for filing, I picked another slide from the same case and started gazing at an area that showed discrete layers of tissue debris covering small patches of the inner surface of the bowel wall. Those are the features of another common type of colitis called pseudomembranous colitis. “Aha! Another diagnosis!” I exclaimed. “Let’s see if I can get someone also to agree with me.” That time I purposefully looked for a third professor and decided not to tell him about the diagnoses made by the other two. I pointed out to him the membrane-like structures and he agreed that we had a case of pseudomembranous colitis. I returned to my desk triumphantly. I knew I had a story to tell. Sometime after that Choua said, “Can you make more slides from that colon and see if you can get another professor to diagnose yet another type of colitis from the same colon?” he challenged. I smiled. Worth a try, I murmured to myself. Read more at:   http://wiki-medical.org/my_ecologic_thinking.htm

New or acute chest symptoms may or may not indicate the presence of a heart problem. One needs an experienced doctor to make that determination and prescribe treatment for it. One cannot be one’s own cardiologist under these conditions.

The second episode of chest symptoms after a negative cardiology evaluation may or may not indicate the presence of a heart problem. Again one needs an experienced doctor to make the diagnosis and treat it appropriately.

Shared Responsibility

The recurrence of similar chest symptoms after that creates an option of a different design: responsibility shared between the doctor and the patient. The doctor continues to treat the problem while the patient can become his assistant, an individual who is willing and able to assume the responsibility of preventing future symptoms. She or he can learn about the nature of the problem, detect the triggers that cause the symptoms, and take simple steps to avoid recurrences of symptoms. This is what I call being one’s own doctor—cardiologist in the current context. It can take several weeks to several months. If the above path of shared responsibility is chosen, I suggest a program of learning from the free video encyclopedia of natural healing offered by Ali Academy (go to Youtube.com and enter Majid Ali, M.D. to reach the channel).

Science, Health, and Healing (SHH) Video Encyclopedia

Our vision of SHH encyclopedia is to provide a public service that is:

* No cost
* Easy to access
* Universally available
* Simple to understand
* Untainted by nefarious corporate influences

Being One’s Own Cardiologist

Safety first. So, do not stop your medication until you have learned well the information presented in SHH video articles in the following area:

* Slow Limbic Breathing to slow down and calm the heart, and to control muscle tightness and slow the heart rate
* Avoidance of sugar, caffeine (from coffee, tea, and colas) to control symptoms
* Gentle, non-competitive spiritual (prayerful) exercise (no huffing and puffing please)
* Control and prevent fermentation in the mind*
* Control and prevent fermentation in the bowel (when that exists)

*Mental fermentation is my term for mental clutter that endlessly processes toxic thoughts and creates mental pollution, rather than mental clarity. Read more at     http://wiki-medical.org/own_cardiologist.htm

HDL cholesterol is dignified cholesterol. LDL cholesterol is naked cholesterol. With these simple words I begin to explain the fundamental difference between what the men of money call “good” cholesterol and “bad” cholesterol. I consider HDL cholesterol dignified because it wears its protein gown elegantly and behaves in dignified and healing ways. I designate LDL cholesterol naked because it lives in rags and readily becomes naked—it is easily oxidized, insulted, roiled, and hurtful, so to speak. I discuss this subject at length in a companion article on the lipid molecular ecosystems in nature, and include brief text from that later in this article.

There Is Only One Cholesterol.

Cholesterol has one molecular formula and one three-dimensional structure. Whether traveling adorned by its protein-gown or un-gowned, it is the same cholesterol. Gowned cholesterol is a guardian angel of cell membranes and facilitates cellular cross-talk. Un-gowned cholesterol is easily insulted—readily oxidized, losing its electron energy in technical language—and strikes back with its lacerating (oxidizing) spears. So the real issue is the availability of protein gowns, which are manufactured in the liver. The problem begins when a liver loaded with pollutants and drug poisons fails to produce the necessary gowns for cholesterol. Every cholesterol molecular is identical. The availability of protein gowns determines how a cholesterol molecule acts. I offer detailed information on this subject in my 90-minute DVD entitled “Cholesterol” available at http://www.majidali.com.

The Liver Makes the Cholesterol Gowns

I anticipate the reader’s question: What organ of the body makes the cholesterol gowns and why do some people have more of them and others have less. The answer: the liver makes nearly all protein gowns for cholesterol. The healthier the liver, the more the production of cholesterol gowns.

The trio of toxicities of foods, environments, and thoughts pollute, poison, and pervert the liver’s ability to make proteins, among them the proteins that serve as gowns for cholesterol. The real culprits is the sordid story of statin drugs are drug tzars. They control doctors to push drugs and control the media to keep the focus away from the issues of liver and the health of its guardian angel, the bowel. Read more at:

 http://www.wiki-medical.org/hdl_cholesterol_dignified.htm

Dignified Cholesterol Prefers Peaceful Company

Natural un-rancid (unoxidized) cholesterol likes the company of un-rancid fats, untangled proteins, and un-sticky sugars. The naked LDL cholesterol, by contrast, surrounds itself by other oxidizing and hurtful substances. This explains why the more HDL one has the more peaceful his endo cells lining one’s blood vessels are. The more oxidized and hurtful LDL cholesterol there is, the more the tissue injury.

Lipoproteins Adorn Cholesterol

A clear knowledge of these basic scientific facts of molecular biology of cholesterol allows everyone to see through the deceptions and distortions of cholesterol monsters, the money men of medicine who keep on their payrolls some medical professors who write editorials and set cholesterol standards. So begins the story of what I consider to be the biggest fraud in American medicine.

No Drugs for Liver Health

Cholesterol cannot flow through the body without being bound to its carrier proteins, that transport it back and forth between the liver, gallbladder, and various cell populations of the body. The liver overloaded with toxins cannot produce enough of the needed proteins, hence the naked and vulnerable proteins. This is the real story of “good” cholesterol” and “bad” cholesterol. Next time you hear it, be amused and pretend that you are most grateful for receiving knowledge about good and bad cholesterol.

There are no drugs—hence no profits—for coaxing the liver to produce enough protein gowns for cholesterol. Profits are in drugs. Cholesterol monsters know how to use TV and newspapers like The New York Times to drown commonsense. Doctors dare not defy the cholesterol standards of the standard-setters—they have children to feed—and people are too frightened to think for themselves.

Evolution’s intelligent Design

Evolution not only created protein gowns for cholesterol but also for cell membranes. This further thickens the plot of the LDL and HDL cholesterol stories. Drs. Brown and Goldstein discovered that cells contain specific receptors for LDL, and that there is a correlation between LDL binding and control of the enzyme that limits cholesterol production in the liver. So,the number of LDL receptors of a cell varies with its requirements for cholesterol. Specifically, cells protect themselves against excess of cholesterol by reducing the number of their LDL receptors and vice versa. A natural consequence of reduced numbers of LDL receptors is decreased cellular uptake of LDL cholesterol and hence, a corresponding rise in blood cholesterol levels. As valuable as these insights into the cholesterol homeostasis are, it is recognized that they do not explain how raised blood cholesterol levels cause vascuclar plaques formation. Read more at:

http://wiki-medical.org/hdl_cholesterol_dignified.htm

The oxygen-starved cells are quickly overloaded with toxins and get covered with cellular grease (see my article The Grease and Detergent Model of Disease for details). This makes memebrane receptors for LDL dysfunctional. The enthusiasts of the cholesterol-plaque-plumbing model of heart disease blissfully ignore all such considerations. What sells statin drugs and coronary procedures is the sordid story of “good” cholesterol” and “bad” cholesterol. There are no drugs—hence no profits—for de-greasing cell membranes and restoring their receptor functions. Profits are in drugs. Cholesterol monsters know how to use medical professors and news media to distort truth. What people need is the knowledge of evolution’s intelligent design and how we can preserve that design with healthful foods, environments, and thoughts. So the fundamental dichotomy between the profitability needs of cholesterol monsters and people seeking healthy hearts.

Cholesterol In Lipid Redox Ecosystem

Below is text from a paper which my colleague, Omar Ali, M.D. and I published in Journal of Integrative Medicine in 1997 to present our view of molecular-ecology of cholesterol:

“Lipids in plasma membranes are essential for membrane fluidity, surface potentials, surface ligand activity, and transport functions. To serve these diverse functions, lipids exist in blood and plasma membranes not as discrete molecular species—as it might seem from the conventional description of the lipid chemistry—but as dynamic “lipid redox ecosystems” in which external pro-oxidant influences are vigorously counterbalanced by antioxidant defenses that exist within the lipid particles. For example, LDL is a large lipoprotein complex that includes the following: cholesterol moieties, apolipoprotein B, neutral and polar lipids including polyunsaturated fatty acids and phospholipids, and lipophilic antioxidant species that include beta carotene and vitamin E. Lipoprotein (a) {Lp [a]} is structurally similar to LDL but is distinguished from it by the presence in it of a highly glycosylated protein designated apoliprotein(a). Lp(a) is considered atherogenic because it is taken up by foam cells, however elevated levels are associated with IHD (ischemic heart disease) in most but not all reports. It binds to apolipoprotein B (apo-B)-containing lipoproteins and proteoglycans.”

In our 1997 article, we addressed the subject of oxidative modification of LDL cholesterol with the following words: “In the past, it has been assumed “that the oxidative modification of LDL occurs primarily in the arterial intima, in microdomains sequestered from antioxidants in plasma.” It has been further assumed that if oxidized LDL were to be generated in the circulating blood, it would be swept up within minutes by the liver168. Hence, all research in atherogenesis has been exclusively directed to investigation of atherogenic changes in vascular wall. It is important to note that these assumptions were made without benefit of direct microscopic observations of the oxidant phenomena in the circulating blood. Those assumptions are clearly not warranted in view of our morphologic observations of oxidative coagulopathy and AA oxidopathy documented in this report. Furthermore, the mechanisms of oxidation of LDL are deemed “unknown.” Here again the fundamental phenomenon of spontaneity of oxidation in the blood ecosystem has been ignored. Our observations also challenge that viewpoint as well as the cholesterol hypothesis of IHD, thus clearing the way for a wholly novel view of pathogenesis of atherogenesis and ischemic coronary artery disease. The clinical implications of this view, as we show in Part-II of this article, are vastly different from those of the prevailing cholesterol theory. “

*Cholesterol rate-limiting enzyme is called HMG CoA (3-hydroxy-3-methyglutaryl coenzyme A) reductase.

END

I present the subject of sex (gonadal) hormon health by raising three questions:

☞ What did my professors and medical textbooks teach me about hormonal balance?
☞ What did evolutionary intelligent design teach me about hormonal homeostasis?
☞ What did my patients—the truest of all my teachers teach me about hormonal healing?

What Did My Professors Teach?

In 1958, my medical professors did one-hormone-one-symptom thinking. They taught us to do the same. They lectured about estrogens, progesterone, and testosterone as single entities, and seldom, if ever, talked about how these pieces fitted into the ever-changing kaleidoscope of the health/dis-ease/disease continuum. Yes, they did teach that too much testosterone is bad for women and execess estrogens are not good for men. Back then, not much was known about the hormone receptor dysfunction—most doctors still do not think of the receptors—so one cannot think unkindly of my professors then. What can one say of medical professors who still do not think of hormone receptors? Or the doctors why never attempt to restore hormone receptor health?

What Did Evolutionary Intelligent Design Teach?

Human beings are energetic-molecular kaleidoscopes in which all pieces—hormones, hormone recptors embedded in cell membranes, and DNA response elements in the present context—sense and respond to the changing needs of all other pieces. When one thing in this kaleidoscope changes in one way, everything changes in some way. Read more at:

http://wiki-medical.org/hormones_five_dimensional.htm

Millions of people worldwide are needlessly administered antibiotics— “antibioticized” seems a more apt term since antibiotics are designer killer molecules. Surprise! Yes, antibiotics are designed to kill life, albeit of microbes initially. This is not cheap dramatization. Let us take the case of Helicobacter pylori (H. Pylori), a bacterium that is considered to be a cause of stomach ulcers. Indeed, a Nobel Prize was awarded to two Australians, Robin Warren and Barry Marshall—a poor choice, in my opinion—for this discovery. Not unexpectedly, the power of the Prize coerced doctors to regularly prescribe antibiotics to kill the bug, even for patients without any symptoms. Doctors happily claimed that they had eradicated the microbe, as evidenced by negative lab tests after antibiotic treatment. So the myth of curing H. Pylori with antibiotics became etched in the marble of medical thinking. My first doubts about this success story arose in the early 1980s when I started using special stain to identify H. Pylori microbes under the microscope in stomach biopsy tissues.
Altered States of Bowel Ecology

In 1980, I published a monograph entitled “Altered States of Bowel Ecology,” in which I focused on ecologic relationships among the various segments of the alimentary tract, using the word “bowel” for the entire tract. I summarized my microscopic observations of several thousand stomach and colon biopsies and argued that a narrow focus on areas of inflammations, infections, and ulceration in the various segments of the tract led to a poor understanding of the changes affecting the whole tract. I also pointed out the poor clinical results obtained with such an approach. I followed that with several chapters published in the syllabi of the instruction courses of American Academy of Environmental Medicine.

The average American child receives 10–20 courses of antibiotics by the time he or she is 18 years old. Linking the ecologic disruptions of the bowel to sugar and antibiotic abuse was not a stretch. Many holistic doctors were raising alarm about what they considered to be the “antibiotic-candida connection.” That also supported, albeit in an indirect way, my notion of altered states of bowel ecology.

Doubts About the Pylori-Ulcer Connection

In the 1980s, I noticed that the tests for H. pylori nearly always became positive months after doctors claimed to have eradicated the microbe with antibiotics. This situation was similar to the case of C. difficile tests which became positive after putative eradication of microbes with antibiotics. I also recognized a close parallel with the case of “candidiasis” treated and “cured” with herbs and antifungal drugs by the practitioners of the so-called alternative medicine. These observations, along with the findings of my microscopic studies formed the basis of my then-rudimentary concept of altered states of bowel ecology. It was in this light that the H. pylori-gastritis-ulcer-cancer risk became increasing suspect in my mind. I regarded the H. Pylori issue as a part of the broader spectrum of gastric ecologic disturbances.

Within several years, some thoughtful and observant physicians became doubtful about the “pylori-ulcer cause-effect relationship and suspected that the microbe “was associated with an increased risk of ulcers and gastric cancer.” Then in 1998, the British Medical Journal published an article arguing that H. pylori might not be a bad microbial actor.

H. pylori, the Dominant Stomach

The title of this article is likely to chagrin some readers who are committed to the use of antibiotics to completely eradicate H. Pylori from the stomach. To allay their concerns, I suggest that they consider the following quote from the prestigious science journal Nature (25 August 2011): “In the early twentieth century, Helicobacter pylori was the dominant microbe in the stomachs of almost all people. By the turn of the twenty-first century, fewer than 6% of children in the United States, Sweden and Germany were carrying the organism. Other factors may be at play in this disappearance, but antibiotics may be a culprit. For example, a single course of amoxicillin or a macrolide antibiotic, most commonly used to treat middle-ear or respiratory infections in children, may also eradicate H. pylori in 20–50% of cases..” Read more at:

http://wiki-medical.org/h__pylori.htm 

Uric acid is entrenched in the medical thinking, as well as in the minds of the general public, as a demon (usual laboratory blood level range : 3.6 to 8.5 mg/dL (~214 µmol/L). It is considered as the:

☞ Cause of gouty arthritis,
☞ Cause of uric acid stones,
☞ Risk factor for hypertension, and
☞ Risk factor for cardiovascular disorders.

The disturbing aspect of this sad story is that people who speak ill of uric acid do not think about its place in evolution’s intelligent design of the human body nor do they study its molecular biology to understand the true significance of changes in its blood levels.

Gout, A Disease of Celebrities

It seems to me that the public infatuation with the ‘disease-of-the-celebrities’ is not a new malady. The mystique of gout has been inculcated and perpetuated throughout history by many celebrities. Alexander the Great, Charlemagne, Benjamin Franklin, Leonardo da Vinci, Newton, and Darwin were among the luminaries who suffered from gout. Their accounts seemed to have fired the imagination of the public about swollen big toes.

Mammals generally have lower serum uric acid levels (0.5 to 1.0 mg/dL) than humans, owing to the existence in them of the enzyme uricase that converts uric acid into allantoin. Our homonoid ancestors lost that enzyme during the Miocene Epoch. Interestingly, it appears that resulted from several parallel mutations which initially involved the promoter region but eventually silenced the whole gene.

Uric Acid Facilitates Dead-Cell-Living-Cell Cross-talk

That uric acid is a principal endogenous danger signal released from dead and dying cells calls for a major shift in the way we look at this molecule. Uric acid stimulates dendritic cells to their maturation. When such cells are co-injected with antigen in vivo, CD8+ T cell responses are significantly enhanced by the generation of responses from CD8+ T cells. Furthermore, in vivo elimination of uric acid inhibits the immune response to antigens associated with dead and dying cells, but that is not the case when antigens are presented by activated dendritic cells.

Read More   at:    http://wiki-medical.org/uric-gout.htm

On November 3, 2011, The New York Times ran a front-page story entitled “Prospect of Delaying Aging Ills Is Raised in Cells Study of Mice.” The article carried two remarkable pictures: (1) a fat mouse sitting next to a thin mouse; and (2) bloated fat cells (of the fat mouse) juxtaposed to normal-sized fat cells of the thin mouse. (Pictures follow later in the text). So, the idea is to fatten the fat cells with a drug to extend the life span. Remarkable, isn’t it?

Good science is good science. In basic sciences, the important discoveries often lead to clinical benefits years or decades later. So, I welcome information about how the genetic pathways of the P16 gene and its related genes—the target of future drugs in the new report—can be altered to prolong life. What surprised me was that the Times completely ignored the obvious problem in its article: All available scientific data worldwide demonstrate that fattened fat cells produce more fattening hormones and obesity increases the risk of all inflammatory and degenerative disorders.

Fattening the Fat Cats

If I were a betting man, I would put a 500-to-one dollar wager against the Times prediction helping any obese people, except those who will rake hundreds of millions of dollars from the Wall Street buzz created by the Times. This, of course, is not the first time the Times would fatten the financial fat cats by its journalistic prowess. Consider how it fattened the fat cats by its reportage of the Leptin fiasco in the following quotes:

The Times Leptin Story August 1, 1995

The discovery of a fat-signaling hormone last week has given new insight into the body’s system of fat control and suggested promising new practical approaches to the treatment of obesity. It may help solve the puzzles of how the body knows how much fat it has and why a person’s weight seems always to be forced back to the set point.

The Times Leptin Story June 15, 1998

A potential anti-obesity drug being developed by Amgen Inc., which made headlines a few years ago by sharply reducing body fat in mice, has now been found to contribute to weight loss in people as well, scientists reported yesterday

The Times Leptin Story Jul 27, 1995

… speculators started buying Amgen’s stock, raising its price by $4.375…

The Times’s Lapdog Joes and Its Untold Leptin-Insulin-Toxicity Story

Altering leptin-associated genetic pathways also causes liver injury (hepatic steatosis), insulin toxicity, Type 2 diabetes, and related metabolic disorders. No, the Times never considered it appropriate to apologize to its readers for hyping the “leptin drug” and fattening the fat cats at the expense of the gullible. The Times has never done a comprehensive review of insulin toxicity —the most important root cause of weight gain, obesity, and Type 2 diabetes—and show how proper diet, spices, herbs, and nutrients can reduce insulin toxicity.

Read more at:  

http://wiki-medical.org/senescent_cells.htm

On page four, the Times noted that the drugged mice in the study had not lived longer than the un-drugged mice